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SAN Blaze Xtreme SAN
Blaze Xtreme

Start Your Own Personal Body Fat Bonfire With Blaze Xtreme.

Blaze Xtreme will safely and rapidly transform your metabolism into a blazing, fat burning inferno. Here are the All-Star MVPs: Delta 5-E, Tyramine, Forskolin, EGCG (a special constituent of green Tea), Bacosides A & B, TTA and Caffeine. This team of superior fat burning compounds work synergistically to obliterate body fat in record time. See below for details.


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Caffeine Diet and Weight Loss Energy/Pre-Workout Fat Burning

Delta 5-E
Delta 5-E (the trademark name for SAN's exclusive 7-Keto-DHEA Ester technology) is a metabolite of DHEA that has an uncoupling effect inside the mitochondria of fat cells (2), so it allows for fat to be easily and readily released from its cell compartment and thus utilized as the preferred source of energy.

Delta 5-E also increases natural thyroid gland production by stimulating the release of the thyroid hormone T3 and the important conversion of T4 to T3 (1) to easily access and destroy fat during exercise. Delta 5-E also coaxes the synthesis of cortisol (3), so it short circuits cortisol's attempt to obscure 6-packs of ripped abs while keeping the immune system strong.

Tyramine
Tyramine makes dieting effortless. Ephedrine worked well for fat burning because it stimulated the neurotransmitter, norepinephrine (NE). The problem is that NE must remain free to circulate in the body to be effective. Tyramine remedies this problem by fitting inside the NE receptor. It takes the "parking space" usually reserved only for NE, so it remains active and torches all the body fat in its path.

Ephedra was never able to take NE's parking space so Tyramine is more effective, much safer and completely legal. Tyramine also supports mood elevation, even during normally trying diets.

Forskolin
Forskolin has been used for over 1000 years, but a recent study proved body fat decreased significantly with a dose of just 500mg of Coleus Forskohlii (10% Forskolin) per day. More amazingly, not only did muscle mass not decline, it actually increased as the fat loss was taking place. The seeming impossibility of burning fat and gaining muscle simultaneously is finally a reality and now available to you in Blaze Xtreme.

Forskolin also increases the overall metabolic rate by stimulating the secretion of T4 from the thyroid and promoting the T4/T3 conversion and may actually supports growth hormone (GH) production (15), which further enhances its fat burning effects.

Forskolin forces body fat to be burned as fuel by activating an enzyme in the fat cell called Hormone Sensitive Lipase (HSL) to release fat to travel where it's needed as fuel primarily to working muscles.

Typically the body requires hormones like epinephrine and NE to bind to fat cell receptors in order to activate HSL. Forskolin overcomes the problem of epinephrine and NE deactivation by mimicking the effects of these fat mobilizing hormones, but bypassing the beta-receptors that normally bind them. Forskolin is able to enter fat cells through the membrane, which increases the levels of Cyclic Adenosine MonoPhosphate (cAMP). The increase in cAMP activates more HSL, which frees up more TG - Triglycerides (fat) to be used as fuel.

Forskolin also increases T3 levels in muscle tissue, which potentiates the "citric acid cycle" (krebs cycle). This forces the fat stored in muscle to be burned without the production of ATP. Normally, ATP must be present as part of the krebs cycle. But Forskolin activates the krebs cycle without ATP, and in the process forces stored fat to be transported to the muscles to be burned as fuel.

Green Tea Extract (EGCG)
Green Tea stimulates fat loss in numerous ways, but because of its caffeine content it works perfectly with Forskolin to prolong the action of cAMP, while amplifying and intensifying the actions of HSL and you need high levels of cAMP to activate HSL.

Norepinephrine (NE) binds to receptors on the surface of fat cells to stimulate the activity of HSL so fat is used as fuel. Unfortunately- under normal conditions- NE is broken down by an enzyme called catechol O-methyltransferase (COMT). This is where green tea comes to the rescue. The catechins (specifically EGCG) in green tea inhibits COMT (5), which prolongs the life and effectiveness of NE.

Green tea is also great for dieting because it's a natural appetite suppressant that increases both NE and dopamine (7). Tea polyphenols can elevate cholecystokinin (CCK), a hormone that suppresses food intake. So green tea simultaneously causes appetite suppression and decreased digestibility of fat.

Caffeine
Caffeine is included in Blaze Xtreme to potentiate the effects of compounds like Tyramine and Forskolin (9). Plus caffeine helps with short-term appetite suppression and fat loss.

Bacopa Moniera (Bacosides A & B)
Bacopa monniera has been used in the Ayurvedic (Hindu) system of medicine for centuries but in a recent study Bacopa extract increased levels of T4 by 41% which means increased metabolic activity for even more dramatic fat loss results. (16)

TTA (Tetradecylthioacetic Acid)
TTA stimulates the breakdown of triglycerides (fat) by signaling the liver to catabolize fatty acids, causing the rapid clearance of fat from the blood stream (11). TTA also completely abolishes diet induced insulin resistance and thus improves insulin sensitivity (12).

References Cited:
1. Clin Chem Lab Med. 2003 Aug; 41(8): 1081-6.
2. Arch Biochem Biophys. 1997 May 1; 341(1): 122-8.
3. Arch Biochem Biophys. 2003 Apr 15; 412(2): 251-8.
4. Int Rev Neurobiol. 2001; 46:79-95.
5. Chantre P, Lairon D, 2002
6. Dulloo AG, Duret C, Rohrer D, Girardier, 1999
7. Yokogoshi H, Kobayashi M, Mochizuki M, 2002
8. Liao S, 2001
9. Crit Rev Food Sci Nutr. 2005; 45(7): 535-62
10. Curr Opin Lipidol. 2002 Jun; 13(3): 295-304.
11. Biochimie. 2005 Jan; 87(1): 15-20
12. J Lipid Res. 2002 May; 43(5): 742-50
13. Obes Res. 2005 Aug; 13(8): 1335-43
14. J Clin Invest. 2001 Sep; 108(5): 733-7
15. Braz J Med Biol Res. 1994 May; 27(5): 1269-72.
16. J Ethnopharmcol. 2002 Jul; 81(2): 281-5
17. J Ethnopharmcol. 1982 Mar; 5(2): 205-14
18. Sabinsa Research, 2004

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